Enzymes & Digestion
In 1974, the first edition of Robbins' Pathologic Basis of Disease alerted us to the fact that
most chronic conditions were associated with inflammation (1). This fact is described
regularly in scientific journals and most commonly in association with heart disease (2).
However, other conditions are associated with chronic inflammation and this includes
disorders of the gastrointestinal tract, and it is now recognized that chronic subclinical
intestinal inflammation is a common feature in ankylosing spondylitis, rheumatoid arthritis,
and other rheumatic conditions (3). The increase in systemic inflammation associated with
aging is also thought to be driven, in part, by chronic intestinal inflammation (3).
The gut has very basic needs in order to remain healthy. Essentially, the gut depends on the
presence of fiber-rich foods, especially vegetables and fruit. A diet without fiber and one that is
excessive in sugar and starch, encourages the development of inflammation, constipation,
and dysbiosis.
To restore gut function and promote systemic health, the appropriate aforementioned foods
should be consumed and supported by key supplements. Most important is to replenish the
gut with healthy bacteria called probiotics - Lactobacillus acidophilus and Bifidobacterium are
the most common. Indeed, healthy aging is thought to be associated with a healthy intestinal
microbiota (3).
Fiber is a crucial component in the diet and the average American consumes less than 50%
of the recommended level. Fiber supplementation is an excellent way to improve intestinal
health and reduce the expression of diverse intestinal conditions (4).
Supplemental digestive enzymes are very beneficial for individuals as they transition to a
healthy diet. Short-term use is typically recommended while probiotics and fiber can be used
as part of a healthy lifestyle.
